Benzoyl peroxide (BPO) is the single best anti-acne topical ingredient according to the American Academy of Dermatology acne treatment guidelines.
There are multiple different types of benzoyl peroxide that differ in their efficacy and side effects. The MDacne products use a special formulation of micronized benzoyl peroxide that is more effective and less irritating than other types of benzoyl peroxide you see in OTC and even prescription products. MDacne products include a micronized formulation of benzoyl peroxide in combination with natural ingredient boosters that provide maximum results with minimal irritation. Thus, the MDacne products that contain benzoyl peroxide are much less drying and more effective than anti-acne ingredients in many prescription and OTC products such as Epiduo or Differin. Having said that, benzoyl peroxide creams main target is mild to moderate acne. People with severe or cystic acne will usually need an additional oral anti-acne treatment such as isotretinoin (Accutane).