Which oral medications can cause darks spots? Hyperpigmentation?

The more common medications that can cause pigmentation:

  • Non-steroidal anti-inflammatory drugs (NSAIDs, e.g., Ibuprofen, Naproxen, Diclofenac)
  • Phenytoin
  • Anti-malarials (e.g. Hydroxychloroquine, Chloroquine)
  • Amiodarone
  • Antipsychotic drugs (e.g., Chlorpromazine)
  • Tetracyclines (most commonly seen with Minocycline)

More info on the best treatment for pigmentation
Dark spots in black skin - best treatment according to Dermatologists
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