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Retinol Treatment System

Perfect Retinol starter kit

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✓ Get the benefits of Retinol without the irritation

✓ Start with Retinol 0.25%, and then move to Retinol 0.5%

✓ Improves the skin’s texture for more youthful-looking skin

✓ Reduces skin blemishes

✓ Targets fine wrinkles and uneven skin tone

✓ Formulated for sensitive, acne-prone skin

✓ Vegan and cruelty-free 

Paraben, sulfate, and silicone-free

✓ Dermatologist designed, tested, and approved



The Retinol Treatment System allows your skin to adjust to Retinol by starting the treatment with Retinol 0.25% and then switching to Retinol 0.5%. It combines the magic of pure Retinol with Niacinamide. Pure Retinol works to unclog pores and prevent acne blemishes and fine wrinkles without over-drying the skin. The Niacinamide (vitamin B3), a powerful anti-inflammatory ingredient, hydrates the skin, improves the skin’s texture, and helps fade post-acne dark spots.

Size: 2 creams, 0.5 oz each

Key Ingredients

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Pure Retinol 0.25% + 0.5%

A powerful Retinoid that is converted in the skin to active Retinoic acid. It increases the skin’s cell turnover, unclogs pores, and helps reduce the appearance of blemishes, fine lines, and wrinkles.


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Niacinamide 2.0% + 4.0%

A form of vitamin B3. It enhances the skin’s protective barrier and helps reduce the appearance of blemishes, large pores, and hyperpigmentation.


Treatment Boosters

🌱 Tea tree oil
Potent antimicrobial and antifungal with proven medical-grade efficacy for acne.

🌿 Aloe Vera leaf extract
A powerful antioxidant that hydrates and reduces redness and irritation.

🌼 Chamomile Extract
An effective antioxidant, anti-bacterial and anti-fungal with potent skin-soothing properties.

🌸 Calendula Officinalis Extract
Highly effective anti-inflammatory and antibacterial compound used by dermatologists to soothe irritated skin.

🌻 Sunflower extract
A powerful ingredient that helps neutralize free radicals and exhibits strong anti-glycation properties. 

🎋 Licorice extract
A potent antioxidant that prevents and helps fade brown spots.


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How to use

Start with your 0.25% Retinol. Apply the Retinol cream at night on clean, dry skin. In the beginning, apply it twice per week, and gradually increase the application frequency. Apply a pea-sized amount to your finger and touch the four areas of your face: forehead, chin, and the two cheeks, avoiding contact with eyes, eyelids, and lips. Always apply sunscreen when outdoors. 

Once you are out of your 0.25% Retinol cream, switch to the 0.5%, Retinol. Keep in mind that it’s 2X more potent. In the beginning, apply it twice per week, and gradually increase the application frequency. 


Retinol products are not recommended for use by pregnant or nursing mothers.

Full ingredients list: Aqua (Deionized Water), Aloe Barbadensis Leaf (Aloe Vera Gel) Juice, Isopropyl Myristate, Glyceryl Stearate, Niacinamide, Stearic Acid, Helianthus annuus (Sunflower) Oil, Polyacrylamide, C13-14 Isoparaffin, Laureth-7, Retinol (Vitamin A), Allantoin, Melaleuca Alternifolia (Tea Tree) Oil, Chamomilla Recutita (Chamomile) Extract, Glycyrrhiza Glabra (Licorice) Extract, Thymus Vulgaris (Thyme) Extract, Calendula Officinalis Extract, Polysorbate 20, Phenoxyethanol, Ethyhexyl glycerin.




Real people and real stories

” My skin has improved so much! The texture of my skin feels amazing, I feel on top of the world. ”

” I love that it helps with the toning of my skin and in reducing the wrinkles, especially the ones on my forehead. It is my first time using this type of product and you can see the difference from before when I relied on typical acne products alone. Overall, this product makes a great addition to any skin routine. "

” My skin has improved so much especially since beginning this new routine. In fact, the retinol has not caused anymore irritation and instead dries out any breakouts I have within days. "

” So far I’ve seen improvement after a week. I noticed my skin is peeling off and my acne scar got lighter. No new pimples at this time. ”


Based on 30 Reviews
Grace Verified BuyerVerified Buyer Verified Reviewer

Retinol is a very nice product

Retinol is a very nice product to help feed any black sport, aging skins, etc… the first-two weeks your skin is going to be dry and all but it gets better. The feeding the spot every quick. Your skin feels clear and smooth once the spots are getting light. Though you may not see any results the first 3 weeks, keep on applying. Patience is key. Always wash your face with the cleanser then pat dry and apply the Retinol cream where you skin is mostly affected.
Carol Verified BuyerVerified Buyer Verified Reviewer

I can not be more delighted with this product

I can not be more delighted with this product,ive tried and tested a lot of acne treatments none of which have helped me the way Mdacne has love the product loce the result 💯💯
Shanaj Verified BuyerVerified Buyer Verified Reviewer

My experience has been amazing with…

My experience has been amazing with MDacne. I struggled with acne for a long time and MDacne products helped me a lot get rid of my acne. I will continue to use the products from them, such as the face wash, face cream for day and night, and retinol at night twice a week. Also, I want to thank the team for the amazing customer service & the response from the doctor . Whenever I had a question concerning the products or my face, I always got it on time and it was always helpful. Thank you MDacne, Regards.
Candice Verified BuyerVerified Buyer Verified Reviewer

MDacne Has Really Helped

MDacne has really helped with my extremely dry skin. It has been a month and it is also starting to clear up my acne that was being caused from the dryness.
Emily Verified BuyerVerified Buyer Verified Reviewer

I do love my retinol cream!

I do love my retinol cream! I’ve struggled with balancing acne care with caring for my aging skin. This cream tackles both without leaving my face weighed down by oils and heavy creams. It takes a little bit for my skin to get used to it, but once it did, it has been a great addition to my regimen. 100% recommend