Products / Retinol 0.5% Treatment Cream

Retinol 0.5% Treatment Cream

Targets acne, refines lines, enhances renewal

Benefits

✓ High-strength 0.5% Retinol concentration
✓ Improves the skin's texture for a more youthful-looking skin
✓ Reduces skin blemishes
✓ Targets fine wrinkles and uneven skin tone
✓ Formulated for sensitive, acne-prone skin
✓ Vegan and cruelty-free
✓ Paraben, sulfate, and silicone-free
✓ Dermatologist designed, tested, and approved

Overview

This unique Retinol treatment cream combines the magic of high-strength 0.5% Retinol and 4% Niacinamide. Pure Retinol works to unclog pores and prevent acne blemishes and fine wrinkles without over-drying the skin. The Niacinamide (vitamin B3), a powerful anti-inflammatory ingredient, hydrates the skin, improves the skin's texture, and helps fade post-acne dark spots.

Size: 0.5 oz | 15 ml

Key Ingredients

Pure Retinol 0.5%
A powerful Retinoid that is converted in the skin to active Retinoic acid. It increases the skin's cell turnover, unclogs pores, and helps reduce the appearance of blemishes, fine lines, and wrinkles.

Niacinamide 4.0%
A form of vitamin B3. It enhances the skin's protective barrier and helps reduce the appearance of blemishes, large pores, and hyperpigmentation.

Treatment Boosters

🌱 Tea tree oil
Potent antimicrobial and antifungal with proven medical-grade efficacy for acne.

🌿 Aloe Vera leaf extract
A powerful antioxidant that hydrates and reduces redness and irritation.

🌼 Chamomile Extract
An effective antioxidant, anti-bacterial and anti-fungal with potent skin-soothing properties.

🌸 Calendula Officinalis Extract
Highly effective anti-inflammatory and antibacterial compound used by dermatologists to soothe irritated skin.

🌻 Sunflower extract
A powerful ingredient that helps neutralize free radicals and exhibits strong anti-glycation properties.

🎋 Licorice extract
A potent antioxidant that prevents and helps fade brown spots.

How to Use

Apply your retinol cream at night on clean, dry skin. In the beginning, apply it twice per week, and gradually increase the application frequency. Apply a pea-sized amount to your finger and touch the four areas of your face: forehead, chin, and the two cheeks, avoiding contact with eyes, eyelids, and lips. Always apply sunscreen when outdoors.

Retinol products are not recommended for use by pregnant or nursing mothers.

Instructions for Women

 

 

 

Instructions for Men

 

 

Full Ingredient List

 

 

 

Aqua (Deionized Water), Aloe Barbadensis Leaf (Aloe Vera Gel) Juice, Isopropyl Myristate, Glyceryl Stearate, Niacinamide, Stearic Acid, Helianthus annuus (Sunflower) Oil, Polyacrylamide, C13-14 Isoparaffin, Laureth-7, Retinol (Vitamin A), Allantoin, Melaleuca Alternifolia (Tea Tree) Oil, Chamomilla Recutita (Chamomile) Extract, Glycyrrhiza Glabra (Licorice) Extract, Thymus Vulgaris (Thyme) Extract, Calendula Officinalis Extract, Polysorbate 20, Phenoxyethanol, Ethyhexyl glycerin.

 

Your questions, answered

What is MDacne Retinol 0.5% Treatment Cream and how does it work?

MDacne Retinol 0.5% Treatment Cream is a high-strength cosmetic night cream with 0.5% pure retinol and 4% niacinamide. Retinol becomes retinoic acid in the skin, increasing cell turnover to help keep pores clear and soften fine lines. Niacinamide hydrates and helps fade post-acne dark spots.

Is MDacne Retinol 0.5% Treatment Cream better than other high-strength retinol creams?

MDacne Retinol 0.5% Treatment Cream buffers its 0.5% retinol with 4% niacinamide, aloe vera, chamomile and calendula, so you get stronger renewal with less of the peeling high-strength retinol usually causes. The cream is vegan, cruelty-free and free of parabens, sulfates and silicones.

MDacne Retinol 0.5% or 0.25% — which retinol strength suits your skin?

MDacne Retinol 0.5% Treatment Cream is best for people who already tolerate retinol well, since it is twice as potent as 0.25%. If your skin is sensitive, dry or new to retinoids, start with MDacne Retinol 0.25% Treatment Cream and move up after a few months.

How long does MDacne Retinol 0.5% Treatment Cream take to work?

MDacne Retinol 0.5% Treatment Cream usually smooths texture and reduces clogged pores within six to eight weeks, with clearer tone and softer fine lines by three months. Because you begin at twice weekly and build up, the first month is mostly your skin adapting.

How do you apply MDacne Retinol 0.5% Treatment Cream at night?

MDacne Retinol 0.5% Treatment Cream goes on at night to clean, dry skin, twice a week to start, increasing slowly. A pea-sized amount covers the whole face: touch forehead, chin and both cheeks, then spread thinly, avoiding eyes, eyelids and lips. Wear sunscreen every morning.

Can MDacne Retinol 0.5% Treatment Cream cause purging or peeling at first?

MDacne Retinol 0.5% Treatment Cream can cause dryness, flaking and a temporary rise in breakouts in the first two to six weeks, as turnover speeds up. Cut back to once a week, moisturize, and rebuild frequency once your skin settles.

Who should not use MDacne Retinol 0.5% Treatment Cream?

MDacne Retinol 0.5% Treatment Cream is not recommended during pregnancy or nursing. Skip this strength if your skin is very reactive or already irritated, and use MDacne Retinol 0.25% Treatment Cream instead. Daily sunscreen is required, since retinol makes your skin more sun-sensitive.

4.5

Based on 49 Reviews
Fola Oluwatosin Verified Customer
This retinol is gentle but effective
This retinol is gentle but effective. My skin looks more even and refined, and I didn’t experience major irritation. It is a good option for gradual improvement and consistent use.
Lauren Verified Customer
Trust the Process MDacne Is Working for Me
I started using MDacne on December 19th, and I began the routine the same day my package arrived. The first thing I tried was the pore patch for my nose (I used it on my cheek area), and I was honestly shocked by how much it pulled out dead skin, dirt, oil, and who knows what else. The next day, my pores already looked smaller and noticeably smoother. After about a week, I started experiencing dryness and peeling. I reached out to Sarah G. from MDacne, and she explained that dryness, tightness, and peeling are completely normal with effective acne treatments. She recommended using an under‑eye cream as a barrier before applying the medicated products, which helped. I also didn’t experience any purging, which was a relief. Overall, my skin is definitely smoother and brighter. My dark marks have started to fade, although the upper cheek area where I had the most clogged pores hasn’t fully lightened yet. I may look into adding a retinol or a dark spot treatment if MDacne recommends it. This isn’t an overnight miracle, but I can genuinely say my skin has improved. You really do have to trust the process. I can honestly say the free trial is worth a shot.
Magan Landry Conner Verified Customer
Customer service is great
Customer service is great. Been using the face wash for 2 months and love the results. Too soon to tell with retinol will update
Nadia “Nads” Lanique Verified Customer
It’s been only a few weeks since I…
It’s been only a few weeks since I started using the customized kit, but I do very much enjoy it. It stopped my large breakouts and I like the balance of different topical treatments between the wash and moisturizers. I will say, it is drying as it suggests but balancing out the right routine and frequency for you will help. 4/5 rating because I still need more time to see how I enjoy the product long term and I also feel like it doesn’t help with my hyperpigmentation, and in some cases it leaves marks from my acne bumps as apart of the process. In this, I can tell it’s working but it’s still something to navigate. I suggest switching between the benzoyl peroxide & retinol at night or including a toning brightener of some sorts to help (again caution to drying and irritation). Always add in products slowly and sparingly to be safe!
Nicole Alston Verified Customer
I am liking my products
I am liking my products. I recently received my order and have a retinol cream as well now that I'm excited about in addition to my acne cream and face wash and moisturizer. My skin is way less oily and much smoother. Im looking forward to clear skin. I have been having some purging.