Products / Retinol Treatment System

Retinol Treatment System

Perfect Retinol starter kit

Benefits

✓ Get the benefits of Retinol without the irritation
✓ Start with Retinol 0.25%, and then move to Retinol 0.5%
✓ Improves the skin's texture for more youthful-looking skin
✓ Reduces skin blemishes
✓ Targets fine wrinkles and uneven skin tone
✓ Formulated for sensitive, acne-prone skin
✓ Vegan and cruelty-free
✓ Paraben, sulfate, and silicone-free
✓ Dermatologist designed, tested, and approved

Overview

The Retinol Treatment System allows your skin to adjust to Retinol by starting the treatment with Retinol 0.25% and then switching to Retinol 0.5%. It combines the magic of pure Retinol with Niacinamide. Pure Retinol works to unclog pores and prevent acne blemishes and fine wrinkles without over-drying the skin. The Niacinamide (vitamin B3), a powerful anti-inflammatory ingredient, hydrates the skin, improves the skin's texture, and helps fade post-acne dark spots.

Size: 2 creams, 0.5 oz each

Key Ingredients

Pure Retinol 0.25% + 0.5%
A powerful Retinoid that is converted in the skin to active Retinoic acid. It increases the skin's cell turnover, unclogs pores, and helps reduce the appearance of blemishes, fine lines, and wrinkles.

Niacinamide 2.0% + 4.0%
A form of vitamin B3. It enhances the skin's protective barrier and helps reduce the appearance of blemishes, large pores, and hyperpigmentation.

Treatment Boosters

🌱 Tea tree oil
Potent antimicrobial and antifungal with proven medical-grade efficacy for acne.

🌿 Aloe Vera leaf extract
A powerful antioxidant that hydrates and reduces redness and irritation.

🌼 Chamomile Extract
An effective antioxidant, anti-bacterial and anti-fungal with potent skin-soothing properties.

🌸 Calendula Officinalis Extract
Highly effective anti-inflammatory and antibacterial compound used by dermatologists to soothe irritated skin.

🌻 Sunflower extract
A powerful ingredient that helps neutralize free radicals and exhibits strong anti-glycation properties.

🎋 Licorice extract
A potent antioxidant that prevents and helps fade brown spots.

How to Use

Start with your 0.25% Retinol. Apply the Retinol cream at night on clean, dry skin. In the beginning, apply it twice per week, and gradually increase the application frequency. Apply a pea-sized amount to your finger and touch the four areas of your face: forehead, chin, and the two cheeks, avoiding contact with eyes, eyelids, and lips. Always apply sunscreen when outdoors.

Once you are out of your 0.25% Retinol cream, switch to the 0.5%, Retinol. Keep in mind that it's 2X more potent. In the beginning, apply it twice per week, and gradually increase the application frequency.

Retinol products are not recommended for use by pregnant or nursing mothers.

Instructions for Women

 

 

 

 

 

 

 

Instructions for Men

 

 

 

 

 

 

Full Ingredient List

 

 

 

 

 

 

 

Aqua (Deionized Water), Aloe Barbadensis Leaf (Aloe Vera Gel) Juice, Isopropyl Myristate, Glyceryl Stearate, Niacinamide, Stearic Acid, Helianthus annuus (Sunflower) Oil, Polyacrylamide, C13-14 Isoparaffin, Laureth-7, Retinol (Vitamin A), Allantoin, Melaleuca Alternifolia (Tea Tree) Oil, Chamomilla Recutita (Chamomile) Extract, Glycyrrhiza Glabra (Licorice) Extract, Thymus Vulgaris (Thyme) Extract, Calendula Officinalis Extract, Polysorbate 20, Phenoxyethanol, Ethyhexyl glycerin.

 

 

 

Your questions, answered

What is the MDacne Retinol Treatment System and how does it work?

The MDacne Retinol Treatment System is a two-cream starter set: 0.25% retinol with 2% niacinamide, followed by 0.5% retinol with 4% niacinamide. You build tolerance on the lower strength, then step up, so you get retinol's renewal with less irritation.

Is the MDacne Retinol Treatment System better than starting retinol on its own?

The MDacne Retinol Treatment System builds in the ramp-up for you, which matters because most people quit retinol after starting too strong and peeling. Finish the 0.25% cream first, then move to the 0.5%, with niacinamide in both to hydrate and calm redness. Best for anyone new to retinol.

MDacne Retinol Treatment System or a single retinol cream — which should you buy?

The MDacne Retinol Treatment System is the better buy if you are new to retinol and want both strengths together, which costs less than buying the two creams separately. Choose a single MDacne retinol cream if you already know which strength your skin tolerates and want to restock it.

How long does the MDacne Retinol Treatment System take to show results?

The MDacne Retinol Treatment System includes two 0.5 oz creams, so the set covers roughly two months. Texture and tone usually improve by week six to eight on the 0.25% cream, and results keep building after you switch to the 0.5%.

How do you use the two creams in the MDacne Retinol Treatment System?

The MDacne Retinol Treatment System starts with the 0.25% cream at night on clean, dry skin, twice weekly, increasing gradually. Use a pea-sized amount across forehead, chin and cheeks. When that cream runs out, switch to the 0.5% and again begin at twice weekly.

Who should not use the MDacne Retinol Treatment System?

The MDacne Retinol Treatment System is not recommended if you are pregnant or nursing, because both creams contain retinol. Expect some dryness or flaking when you start each strength, and lower the frequency until it passes. Wear sunscreen daily, because retinol makes skin more sensitive to sun.

4.5

Based on 49 Reviews
Fola Oluwatosin Verified Customer
This retinol is gentle but effective
This retinol is gentle but effective. My skin looks more even and refined, and I didn’t experience major irritation. It is a good option for gradual improvement and consistent use.
Lauren Verified Customer
Trust the Process MDacne Is Working for Me
I started using MDacne on December 19th, and I began the routine the same day my package arrived. The first thing I tried was the pore patch for my nose (I used it on my cheek area), and I was honestly shocked by how much it pulled out dead skin, dirt, oil, and who knows what else. The next day, my pores already looked smaller and noticeably smoother. After about a week, I started experiencing dryness and peeling. I reached out to Sarah G. from MDacne, and she explained that dryness, tightness, and peeling are completely normal with effective acne treatments. She recommended using an under‑eye cream as a barrier before applying the medicated products, which helped. I also didn’t experience any purging, which was a relief. Overall, my skin is definitely smoother and brighter. My dark marks have started to fade, although the upper cheek area where I had the most clogged pores hasn’t fully lightened yet. I may look into adding a retinol or a dark spot treatment if MDacne recommends it. This isn’t an overnight miracle, but I can genuinely say my skin has improved. You really do have to trust the process. I can honestly say the free trial is worth a shot.
Magan Landry Conner Verified Customer
Customer service is great
Customer service is great. Been using the face wash for 2 months and love the results. Too soon to tell with retinol will update
Nadia “Nads” Lanique Verified Customer
It’s been only a few weeks since I…
It’s been only a few weeks since I started using the customized kit, but I do very much enjoy it. It stopped my large breakouts and I like the balance of different topical treatments between the wash and moisturizers. I will say, it is drying as it suggests but balancing out the right routine and frequency for you will help. 4/5 rating because I still need more time to see how I enjoy the product long term and I also feel like it doesn’t help with my hyperpigmentation, and in some cases it leaves marks from my acne bumps as apart of the process. In this, I can tell it’s working but it’s still something to navigate. I suggest switching between the benzoyl peroxide & retinol at night or including a toning brightener of some sorts to help (again caution to drying and irritation). Always add in products slowly and sparingly to be safe!
Nicole Alston Verified Customer
I am liking my products
I am liking my products. I recently received my order and have a retinol cream as well now that I'm excited about in addition to my acne cream and face wash and moisturizer. My skin is way less oily and much smoother. Im looking forward to clear skin. I have been having some purging.